Acute antagonism of dopamine D2-like receptors by amisulpride: Effects on hormone secretion in healthy volunteers
References (39)
- et al.
Dopamine D3 receptor mRNA and binding sites in human brain
Brain Research and Molecular Brain Research
(1993) - et al.
Molecular biology of dopamine receptors
Trends in Pharmacological Sciences
(1992) - et al.
Distribution of dopamine D2 receptor mRNA splice variants in the rat by solution hybridization/protection assay
Neuroscience Letters
(1991) - et al.
Acute dopaminergic blockade by sulpiride stimulates β-endorphin secretion in pregnant women
Clinical Endocrinology
(1984) - et al.
Missing indicator function of growth hormone and luteinizing hormone blood levels for dopamine and serotonin concentration in the human brain
Journal of Neural Transmission
(1973) - et al.
Circadian and pulsatile thyrotropin secretion in euthyroid man under the influence of thyroid hormone and glucocorticoid administration
Journal of Clinical Endocrinology and Metabolism
(1987) - et al.
Place de l'amisulpride dans le groupe des benzamides substitués
Actualités Psychiatriques
(1986) - et al.
L-Dopa releases GH via GRF dependent mechanism in normal human subjects, whereas arginine, clonidine and adrenaline plus propanolol do not
- et al.
Dopaminergic and cholinergic influences on the growth hormone response to growth hormone-releasing hormone in man
Neuroendocrinology
(1987) - et al.
Circadian rhythm of basal growth hormone in man
Journal of Clinical Endocrinology and Metabolism
(1983)
Pharmacocinétique et métabolisme de l'amisulpride
Annales de Psychiatrie
Neuroendocrine profile of SDZ HDC-912 and OPC-4392, two new anti-psychotic drugs, in schizophrenic patients
Psychopharmacology
Dopamine receptors on intact anterior pituitary cells in culture: functional association with the inhibition of prolactin and thyrotropin
Endocrinology
Further studies on dopamine-induced suppression of pulsatile LH release in ovariectomized rats
Neuroendocrinology
Biological tolerance of amisulpride with long-term treatment
Neuroleptics and neuroendocrine function
Annual Review of Pharmacology and Toxicology
Effects of oestradiol benzoate and progesterone on luteinizing hormone release and catecholamine turnover in the preoptic-hypothalamic brain area of of ovariectomized rats
Journal of Endocrinology
Multifactorial control of pituitary hormone secretion: the “wheels” of the brain
Synapse
Multiple dopamine receptors in brain and the pharmacological action of substituted benzamides
Acta Psychiatrica Scandinavica
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Thyroid hormones in persons with schizophrenia: A systematic review and meta-analysis
2021, Progress in Neuro-Psychopharmacology and Biological PsychiatryCitation Excerpt :Similarly, a large retrospective cohort study demonstrated that acute treatment with quetiapine is strongly associated with the development of new-onset hypothyroidism (Zhao et al., 2021). Other studies have shown that phenothiazine and amisulpride may increase the levels of TSH after stimulation by thyrotropin-releasing hormone (TRH) (Gründer et al., 1999; Khalil and Richa, 2011; Wetzel et al., 1994; Zatelli et al., 2014). In turn, clozapine has been found to decrease TRH-stimulated level of TSH (Paunovlć et al., 1991).
Effects of antipsychotics on circadian rhythms in humans: a systematic review and meta-analysis
2021, Progress in Neuro-Psychopharmacology and Biological PsychiatryCitation Excerpt :Five of these studies used atypical AP. In contrast, another five RCTs with 112 individuals on AP and 69 with no AP reported no difference in cortisol levels as measured from plasma, saliva or urine between individuals on AP and placebo (Cohrs et al., 2006; de Koning and de Vries, 1995; Handley et al., 2016; von Bahr et al., 1991; Wetzel et al., 1994). Among these five articles, four RCTs used atypical AP (de Koning and de Vries, 1995, Handley et al., 2016, von Bahr et al., 1991, Wetzel et al., 1994).
Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication
2018, Journal of Psychiatric ResearchCitation Excerpt :Of second-generation drugs, mainly amisulpride, quetiapine and clozapine have been studied regarding thyroid function (Bou Khalil and Richa, 2011). Use of quetiapine has been linked to cases of hypothyroidism (Feret and Caley, 2000; Kontaxakis et al., 2009), amisulpride to elevated TRH-stimulated TSH (Grunder et al., 1999; Wetzel et al., 1994) whereas clozapine has been associated with reduced TRH-stimulated TSH concentration (Paunovic et al., 1991). Also aripiprazole has been linked to thyroid abnormalities in combinations with olanzapine (Ohta et al., 2017) and sertraline (Church and Callen, 2009).
Effects of antipsychotics on cortisol, interleukin-6 and hippocampal perfusion in healthy volunteers
2016, Schizophrenia ResearchCitation Excerpt :Amongst other unique pharmacological properties that separate aripiprazole from other SGAs, this drug has a lower affinity for 5HT-2 than for D2 receptors (Mamo et al., 2007). It is interesting to note that amisulpride, the only SGA that has a similarly lower affinity for 5HT-2 than D2 receptors, has also been associated with an absence of effect on cortisol in healthy individuals (Wetzel et al., 1994), suggesting that the dopamine-serotonin affinity profile common to these drugs, and not other SGAs, might be important in HPA axis regulation. Together with the haloperidol effects evident in our study, this indicates that it is not only the affinity to dopamine receptors that is key in the regulation of stress and pro-inflammatory markers, but also the function of that drug on dopamine receptors (i.e. antagonistic vs partial agonism).
Differential add-on effects of aripiprazole in resolving hyperprolactinemia induced by risperidone in comparison to benzamide antipsychotics
2010, Progress in Neuro-Psychopharmacology and Biological PsychiatryAmisulpride-induced hyperprolactinemia is reversible following discontinuation
2007, Progress in Neuro-Psychopharmacology and Biological Psychiatry