Assessing posttraumatic stress related impairment and well-being: The Posttraumatic Stress Related Functioning Inventory (PRFI)
Introduction
Posttraumatic stress disorder (PTSD) has been highlighted as a signature wound of the conflicts in Afghanistan (Operation Enduring Freedom) and Iraq (Operation Iraqi Freedom; OIF; Operation New Dawn; OND), with rates of PTSD found to vary between 11% and 22% among veterans who served in these operations (Milliken et al., 2007, Seal et al., 2007). While a great deal of attention has been placed on the suffering associated with PTSD symptoms, less emphasis has been given to the equally important impact these symptoms have on the daily lives of veterans, in particular on their capacity to thrive at work or school and to develop, maintain and enjoy personal relationships. Indeed, it is well-established that PTSD symptoms are linked to difficulties in functioning across a number of life domains, including social and occupational functioning (Larson and Norman, 2014, Jakupcak et al., 2008, Beckham et al., 1997, Thorp and Stein, 2005, Prigerson et al., 2001, Rodriguez et al., 2012, Schnurr et al., 2009). Results from the National Vietnam Veterans Readjustment Study (NVVRS) found that veterans with PTSD, compared with combat exposed veterans without PTSD, had more interpersonal difficulties, greater occupational instability, poorer physical health, and greater medical service utilization (Kulka et al., 1990). Further analyses with this sample found that PTSD predicted poorer outcome in physical health, employment, and diminished well-being, over and above comorbid psychiatric and other medical disorders (Zatzick et al., 1997). Other studies examining interpersonal relationships among veterans with PTSD reported worse family relationships (Koenen et al., 2008), difficulties in intimacy and communication, and higher rates of separation and divorce (Riggs et al., 1998, Cook et al., 2004).
Assessment of PTSD-related functioning has been recommended for improved PTSD diagnostic accuracy, treatment, and assessment of treatment outcome (Rodriguez et al., 2012). The direct relationship of PTSD symptoms to social and occupational functioning and general quality of life is clouded by other conditions that commonly co-occur in individuals with PTSD, such as depression and substance use disorders. Moreover, variation in functioning among those with PTSD symptoms has been observed, such that some individuals with relatively mild severity of PTSD symptoms report substantial functional difficulties (e.g., McLaughlin et al., 2015, Pietrzak et al., 2009) while others with high symptom levels have reported positive changes in psychological and functional outcomes (e.g., relationship closeness; see Linley and Joseph, 2004 for review). This lack of a perfect correspondence between level of PTSD symptoms and functional impairment suggests a need for more precise assessment and a deeper understanding of this relationship. Further, general assessments of functioning do not determine the extent to which functioning difficulties are directly related to PTSD symptoms. Unfortunately, this can lead to mistaken assumptions regarding the impact of PTSD, versus other factors or co-morbid conditions, on social and occupational functioning and leave unanswered the question about the degree to which difficulties in functioning or poor quality of life are attributable to PTSD symptoms.
We have developed a self-report measure, the Posttraumatic Stress Related Functioning Inventory (PRFI), to begin to address this gap in knowledge. This brief measure is intended to provide a means for those providing psychiatric and psychological care to patients with PTSD to better understand the perceived impact of symptoms on social and occupational functioning and quality of life (i.e., lifestyle) and to indicate points of intervention. For this study we examined the psychometric properties of the PRFI utilizing data collected within a larger study examining quality of life and functioning in 251 OEF/OIF/OND veterans with PTSD symptoms. We also examined one-year test-retest reliability of the measure in a subset of the baseline sample (N = 109) who received a second administration of the PRFI.
Section snippets
Participants
Baseline. As noted previously, these data were collected as a component of a larger VA-funded study examining factors related to difficulties in functioning among veterans who served in OEF/OIF/OND. Participants were 251 male and female OEF/OIF/OND veterans who were initially screened using a PTSD self-report measure, the Posttraumatic Stress Checklist – Military (PCL-M) over the telephone and at the time of study entry met DSM-IV criteria for subthreshold (2 out of 3 symptom clusters) or full
Demographic characteristics and functioning
See Table 2, Table 3 for PRFI baseline sample item and subscale means and standard deviations. Table 4 presents the relationships between demographic characteristics and PTSD-related functioning at baseline. Of note, more severe impact of PTSD symptoms on all functional domains, with the exception of two correlations that did not meet statistical significance (notably race/ethnicity with social relationships (SCI) and combat exposure with work/school (TSI)) was observed for those of
Discussion
This study introduced and conducted an initial examination of the psychometric properties of a new self-report assessment of functional impairment related to posttraumatic stress symptoms. Overall, these initial findings indicate that the PRFI has acceptable validity and reliability, and has promising utility as a measure of PTSD-related impairment. In general, the veterans who participated in this study had been exposed to significant levels of combat, experienced symptoms of depression,
Contributors
Drs. McCaslin and Maguen co-authored the PRFI measure. Dr. McCaslin designed the study. Drs. Marmar and Neylan provided key feedback and consulted on both the measure development and the research study. Ms. Bosch managed the study data. Drs. McCaslin, Maguen, and Mr. Metzler undertook statistical analyses. Dr. McCaslin wrote the first draft of the manuscript. All authors contributed to and have approved the final manuscript.
Role of funding source
This work was supported by Career Development Award (CDA-2-032-06F: McCaslin) from the United States (U.S.) Department of Veterans Affairs, Clinical Sciences Research and Development Service and Career Development Award (RCD 06-042: Maguen) from the United States (U.S.) Department of Veterans Affairs, Health Services Research and Development Service.The contents do not represent the views of the U.S. Department of Veterans Affairs or the United States Government.
Conflicts of interest
Dr. Neylan has received research medications from Actelion and Glaxo Smith Kline for studies funded by the Department of Defense and Department of Veterans Affairs and has consulted for Genentech. None of the other authors have any conflicts of interest to disclose.
Acknowledgments
We thank the veterans who participated in this research. This research was supported by VA Clinical Sciences Research and Development Career Development Award (CDA-2-032-06F: McCaslin) and VA Health Services Research and Development Career Development Award (RCD 06-042: Maguen). The contents do not represent the views of the U.S. Department of Veterans Affairs or the United States Government. We are grateful to John McQuaid, Ph.D., Julie Dinh, B.A., Gary Tarasovsky, B.S., and Torsten Neilands,
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